Neurosurgery Clinical Trials & Research Protocols at Greenwich Hospital

Neurosurgery Clinical Trials & Research Protocols at Greenwich Hospital
Patients who qualify have access at Greenwich Hospital to national clinical trials and research focusing on the latest treatment protocols.

What are Clinical Trials?

Research studies as of October 2011

Connecticut Lumbar Interbody Fusion (CLIF) Registry
Greenwich Hospital has begun enrollment in a prospective, non-randomized registry designed to evaluate clinical outcomes in Connecticut patients treated with single-level instrumented lumbar interbody fusion. Patients must have been consecutively treated by spine surgeons in both academic and private practice environments.

The registry’s primary aim is to establish a statewide, multi-center, cooperative research group of academic and private practice spine surgeons that demonstrate at least 80 percent compliance in collecting 1-year outcomes data for this particular type of fusion. The secondary aim is to demonstrate clinical effectiveness for the procedure.

Ten sites are participating in the study. Each patient will be followed for 12 months after surgery.

Principal Investigator: Andrea F. Douglas, MD, Neurosurgeon at Greenwich Hospital

Scoliosis Registry
The purpose of establishing an adult degenerative scoliosis registry is to better understand the long term functional and quality of life outcomes of both nonsurgical and surgical treatment options for patients with scoliosis. Outcome questionnaires will be filled out before and after starting treatment for a period of 24 months.

Principal Investigator: Andrea F. Douglas, MD, Neurosurgeon at Greenwich Hospital

Neuropoint-SD Study
This is a prospective, multi-center registry that collects comparative effectiveness outcomes for degenerative spine diseases after surgical treatment. It uses this data to demonstrate clinical effectiveness for two common lower back surgical procedures: lumbar discectomy and lumbar fusion. Outcome questionnaires are completed before surgery and after surgery for one year.

Principal Investigator: Andrea F. Douglas, MD, Neurosurgeon at Greenwich Hospital

Greenwich Lumbar Stenosis SLIP Study
Lumbar Stenosis: The Greenwich Lumbar Stenosis SLIP Study is a prospective, randomized multi-center trial to determine the optimal use of lumbar spinal instrumentation and fusion in patients with single-level degenerative grade I spondylolisthesis and symptomatic lumbar spinal stenosis. All patients are eligible to obtain a free review of their images from a panel of distinguished spinal surgeons from across the country. Outcome questionnaires are completed before surgery and after surgery for 5 years. We are no longer enrolling new patients in this study because we have reached our accrual goal.

Principal Investigator: Zoher Ghogawala, MD, Neurosurgeon at Greenwich Hospital

Cervical Spondylotic Myelopathy Study (CSM)
Cervical Spondylotic Myelopathy: The CSM Study is a prospective, multi-center trial to determine the optimal surgical approach (front versus back) for patients with multi-level cervical spondylotic myelopathy. All patients are eligible to obtain a free review of their images from a panel of distinguished spinal surgeons from across the country. Outcome questionnaires are completed before surgery and after surgery for one year. We are no longer enrolling new patients in this study because we have reached our accrual goal.

Principal Investigator: Zoher Ghogawala, MD, Neurosurgeon at Greenwich Hospital

Cognitive Outcome After Carotid Surgery Study
The Cognitive Outcome After Carotid Surgery Study is a non-randomized study to evaluate changes in cognitive function in patients undergoing carotid revascularization. Neuropsychological tests will be given pre and post operatively at one month and one year.

Principal Investigator: Zoher Ghogawala, MD, Neurosurgeon at Greenwich Hospital

For more information: Please e-mail Ellyn Wasserberger, Neuroclinical Research Manager, or call 203-863-3474.